Selected Publications

Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma

Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma

9 July 2020

PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis.

PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis.

30 June 2020

A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models

A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models

26 June 2020

Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development

Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development

7 April 2020

The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children: a review

The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children: a review

1 February 2020

The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness

The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness

14 January 2020

SMARTer single cell total RNA sequencing

SMARTer single cell total RNA sequencing

19 September 2019

Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes

Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes

5 April 2019

Purification of high-quality RNA from a small number of fluorescence activated cell sorted zebrafish cells for RNA sequencing purposes

Purification of high-quality RNA from a small number of fluorescence activated cell sorted zebrafish cells for RNA sequencing purposes

20 March 2019

DREAM target reactivation by core transcriptional regulators supports neuroblastoma growth

DREAM target reactivation by core transcriptional regulators supports neuroblastoma growth

3 February 2019

Long noncoding RNA expression profiling in cancer: Challenges and opportunities

Long noncoding RNA expression profiling in cancer: Challenges and opportunities

20 January 2019

ALK positively regulates MYCN activity through repression of HBP1 expression

ALK positively regulates MYCN activity through repression of HBP1 expression

11 December 2018

A mechanistic classification of clinical phenotypes in neuroblastoma

A mechanistic classification of clinical phenotypes in neuroblastoma

7 December 2018

Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients

Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients

6 December 2018

In silico discovery of a FOXM1 driven embryonal signaling pathway in therapy resistant neuroblastoma tumors

In silico discovery of a FOXM1 driven embryonal signaling pathway in therapy resistant neuroblastoma tumors

30 November 2018

Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma

Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma

20 November 2018

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

19 November 2018

A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing

A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing

28 June 2018

Network Modeling of microRNA-mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN

Network Modeling of microRNA-mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN

15 June 2018

Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia

Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia

18 April 2018

Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients

Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients

5 March 2018

The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease

The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease

2 February 2018

Epigenetic regulation of neuroblastoma development

Epigenetic regulation of neuroblastoma development

2 February 2018

Early and late effects of pharmacological ALK inhibition on the neuroblastoma transcriptome

Early and late effects of pharmacological ALK inhibition on the neuroblastoma transcriptome

5 December 2017

Shallow Whole Genome Sequencing on Circulating Cell-Free DNA Allows Reliable Noninvasive Copy-Number Profiling in Neuroblastoma Patients

Shallow Whole Genome Sequencing on Circulating Cell-Free DNA Allows Reliable Noninvasive Copy-Number Profiling in Neuroblastoma Patients

14 July 2017

T-ALL and thymocytes: a message of noncoding RNAs

T-ALL and thymocytes: a message of noncoding RNAs

7 March 2017

Stage 4S neuroblastoma tumors show a characteristic DNA methylation portrait

Stage 4S neuroblastoma tumors show a characteristic DNA methylation portrait

6 September 2016

Long noncoding RNA signatures define oncogenic subtypes in T-cell acute lymphoblastic leukemia

Long noncoding RNA signatures define oncogenic subtypes in T-cell acute lymphoblastic leukemia

10 May 2016

Neuroblastoma: A Tough Nut to Crack

Neuroblastoma: A Tough Nut to Crack

1 January 2016

Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment

Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment

15 July 2015

MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma

MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma

26 June 2015